What are the differences between seminoma and Spermatocytic tumor?
What are the differences between seminoma and Spermatocytic tumor?
Clinically, the main difference between spermatocytic and classical seminoma is the age of occurrence. Spermatocytic seminoma tends to occur more commonly, in men aged over 50, while in classical seminoma, the age at diagnosis is between 25 and 40 years.
What is testicular sarcoma?
Paratesticular sarcomas are defined as tumors that arise within the scrotum and include the subsites of epididymis, spermatic cord, and tunica vaginalis and represent the most common type of GU sarcoma.
Is seminoma malignant tumor?
Seminoma is a malignant germ cell tumor that involves most commonly the testicle or less frequently the mediastinum, the retroperitoneum, or other extra-gonadal sites. They are common among men ages 15-34 years old.
Is testicular seminoma cancer?
Seminoma: This is a slow-growing form of testicular cancer found in men in their 40s and 50s. The cancer is in the testes, but it can spread to the lymph nodes. Lymph node involvement is either treated with radiotherapy or chemotherapy. Seminomas are very sensitive to radiation therapy.
Is Spermatocytic tumor malignant?
Spermatocytic tumor is a rare, malignant neoplasm of the testes. Since the prognosis for this tumor type is favorable, accurate diagnosis and differentiation from other malignant testicular neoplasms (classic seminoma and lymphoma) are crucial.
Is seminoma cancer aggressive?
They occur most often in men in their 40s. Anaplastic seminomas are more aggressive and are more likely to metastasize to other parts of the body.
What is Spermatocytic tumor?
Spermatocytic tumor is a rare malignancy that accounts for 0.61% of testicular germ cell tumors[1]. Tumor development is independent of ethnicity and a history of cryptorchidism. Older men with an average age of 52 years are often the most affected[2].
How is seminoma treated?
Treatment of seminoma may include the following: Surgery to remove the testicle, followed by surveillance. For patients who want active treatment rather than surveillance, treatment may include: Surgery to remove the testicle, followed by chemotherapy.
What is metastatic seminoma?
Abstract. Retroperitoneal metastasis of seminoma often occurs in the higher stage through lymph nodes. Generally, seminoma expresses specific germ cell markers while being negative for carcinoma markers. We present a unique case of cytokeratin positive seminoma initially presented as retroperitoneal metastasis.
Is dysgerminoma curable?
[1,2] Chemotherapy with bleomycin, etoposide, and cisplatin (BEP) can cure the majority of such patients. Stage IV dysgerminoma is not treated with radiation therapy, but rather with chemotherapy, preferably with three to four courses of cisplatin-containing combination chemotherapy such as BEP.
Can you survive sarcoma?
The overall 5-year survival rate for sarcoma is 65%. About 60% of sarcomas are found as a localized sarcoma. The 5-year survival rate for people with localized sarcoma is 81%. About 18% of sarcomas are found in a locally advanced stage.
How is dysgerminoma treated?
Treatment of dysgerminoma may be either: total abdominal hysterectomy and bilateral salpingo-oophorectomy followed by radiation therapy or combination chemotherapy; or. unilateral salpingo-oophorectomy followed by chemotherapy.
What is spermatocytic tumor?
Spermatocytic tumor is a rare, malignant neoplasm of the testes. Since the prognosis for this tumor type is favorable, accurate diagnosis and differentiation from other malignant testicular neoplasms (classic seminoma and lymphoma) are crucial.
What is Spermatocytic seminoma (SS)?
Spermatocytic seminomas (SSs) are unique among GCTs in terms of older age at presentation and their lack of association with other GCTs and the usual risk factors of GCT (cryptorchid testis and dysgeneses). Spermatocytic seminoma accounts for fewer than 5% of all testicular tumors.
What is the prevalence of spermatocytic seminoma?
Spermatocytic seminoma is an uncommon testicular neoplasm that behaves in an indolent fashion. It comprises about 5% of testicular seminomas.94 The histogenesis, clinical presentation, morphological features, and the biological behavior of spermatocytic seminoma bear no resemblance to classical seminoma.
Can we make a differential diagnosis of spermatocytic tumor?
At present, as spermatocytic tumors are extremely rare, there is a paucity of data for clinicians and pathologists to make differential diagnosis. Herein, we present a case of spermatocytic tumor, and review and consult the relevant literature.