What is the drug of choice for tonic-clonic seizure?

What is the drug of choice for tonic-clonic seizure?

For generalised tonic-clonic seizures, sodium valproate is recommended as first-line treatment. If this is unsuitable, lamotrigine is recommended. Carbamazepine and oxcarbazepine can be considered as alternatives.

What are tonic-clonic seizures caused by?

A grand mal seizure — also known as a generalized tonic-clonic seizure — is caused by abnormal electrical activity throughout the brain. Usually, a grand mal seizure is caused by epilepsy.

What are the signs and symptoms of tonic-clonic seizure?

Tonic-clonic seizures

  • tonic stage – you lose consciousness, your body goes stiff, and you may fall to the floor.
  • clonic stage – your limbs jerk about, you may lose control of your bladder or bowel, you may bite your tongue or the inside of your cheek, and you might have difficulty breathing.

How serious is a tonic-clonic seizure?

A tonic-clonic seizure that lasts longer than 5 minutes needs immediate medical help. Call 911 for emergency help. A seizure that lasts more than 5 minutes, or three seizures in a row without the person coming to between them, is a dangerous condition.

Do tonic-clonic seizures cause brain damage?

Most types of seizures do not cause damage to the brain. However, having a prolonged, uncontrolled seizure can cause harm. Because of this, treat any seizure lasting over 5 minutes as a medical emergency.

Which is a first line medication for generalized tonic clonic seizures?

Table 2

Primary Generalized Tonic–Clonic Seizures Partial Seizures* Atypical Absence Myoclonic, and Atonic Seizures
First-line agents
Valproic acid Lamotrigine Topiramate Carbamazepine Phenytoin Oxcarbazepine Valproic Acid Valproic acid Lamotrigine Topiramate
Alternative agents

What is the strongest seizure medication?

“[Lamictal] seems to be the winner,” Marson says. The second trial looked at 716 patients newly diagnosed with generalized epilepsy. It compared the older drug valproic acid (in the U.S., Depakote is the most popular member of this drug family) to Lamictal and Topamax.

Are tonic-clonic seizures life threatening?

A tonic-clonic seizure usually lasts one to three minutes, but may last up to five minutes. If seizures last more than five minutes, or occur one after another without recovery between seizures, the individual may be experiencing a life-threatening medical emergency and requires immediate medical help.

What should you not do during a tonic-clonic seizure?

Do not attempt to hold the person still. Do not put anything in the person’s mouth. It is physically impossible to swallow one’s tongue, and putting things in the mouth may lead to injury. Time the seizure.

Can tonic-clonic seizures be fatal?

Tonic-clonic seizures are a severe type of epileptic seizure. These can cause sudden loss of consciousness, convulsions, and loss of bladder control. The chance of sudden death is also higher in individuals whose seizures begin at a young age. However, unexpected death is extremely uncommon in young children.

What is the safest anti seizure medication?

Do tonic seizures cause brain damage?

Is a tonic-clonic seizure a medical emergency?

Do tonic clonic seizures cause brain damage?

Can your heart stop during a seizure?

The electrical activity in the brain during a seizure can also change our pulse and usually causes an increase in heart rate. However, during some seizures, the heart can slow or even stop temporarily, which is referred to as ictal asystole.

What is a tonic-clonic seizure?

Tonic-clonic seizures, involve both tonic (stiffening) and clonic (twitching or jerking) phases of muscle activity. Tonic-clonic seizures may start with a simple partial seizure or aura. The person may experience changes in sensation, mood or emotion leading up to the tonic-clonic seizure.

What should I do if I Witness a tonic-clonic seizure?

Witnessing a person having a tonic-clonic seizure can be upsetting, but it’s important to remember that most seizures resolve on their own after one to three minutes. To offer assistance: Protect the person from injury by helping them to the floor and clearing away furniture or other items.

What are tonic seizures in Lennox-Gastaut syndrome?

People with Lennox-Gastaut syndrome or other types of epilepsy with mixed seizures are most likely to have tonic seizures, but they can happen to anyone. Clonic seizures are characterized by repeated jerking movements of the arms and legs on one or both sides of the body, sometimes with numbness or tingling.

Can a clonic seizure happen on both sides of the brain?

1 Tonic and clonic seizures can start on one side of the brain (partial or focal seizures), or on both sides of the brain simultaneously (generalized). 2 Tonic and clonic seizure activity can happen in the same seizure. 3 If someone near you has a seizure: Do not put anything in the person’s mouth.