Is INH used to treat TB?
Is INH used to treat TB?
The most common medications used to treat tuberculosis include: Isoniazid. Rifampin (Rifadin, Rimactane) Ethambutol (Myambutol)
How many categories of TB treatment are there?
Tuberculosis can be cured. Directly Observed Treatment, Short- course (DOTS) is the most effective way to ensure cure. There are three categories of treatment: Categories I, II and III and each has an Intensive Phase and Continuation Phase.
Is isoniazid the same as INH?
Isoniazid, also known as isonicotinic acid hydrazide (INH), is an antibiotic used for the treatment of tuberculosis. For active tuberculosis it is often used together with rifampicin, pyrazinamide, and either streptomycin or ethambutol. For latent tuberculosis it is often used by itself.
What is the gold standard for TB diagnosis?
Nucleic Acid Amplification (NAA) Test Culture remains the gold standard for laboratory confirmation of TB disease, and growing bacteria are required to perform drug-susceptibility testing and genotyping.
What is INH used for?
Isoniazid is used to treat tuberculosis (TB) or prevent its return (reactivation). It may be given alone, or in combination with other medicines, to treat TB or to prevent its return (reactivation). This medicine may also be used for other problems as determined by your doctor.
What are the side effects of INH?
Common side effects of isoniazid include:
- numbness and tingling in the extremities,
- hepatitis (symptoms include loss of appetite, nausea, vomiting, fatigue, malaise, and weakness),
- nausea,
- vomiting,
- upset stomach,
- fever, or.
- rash.
What is the classification of tuberculosis?
Childhood tuberculosis (TB) has been conventionally classified as pulmonary TB (PTB) and extrapulmonary TB (EPTB) disease. The latter traditionally includes disseminated forms of disease such as tuberculous meningitis and miliary disease.
What is more accurate PPD or QuantiFERON?
The interferon-gamma is then measured using ELISA technology. In laymen’s terms, that means the QuantiFERON test has a high degree of reliability. It also prevents the false positive readings common with PPDs. Though a more expensive test, the QuantiFERON on average saves 4 days of waiting time.
How long do you take INH?
If you have TB infection, you will probably just take INH (Isoniazid) for 6 to 9 months, or you may take INH and Rifapentine (RPT) for 3 months. Together, you and your doctor will decide which medicine is right for you.
How long is INH therapy?
Treatment Regimens for Latent TB Infection (LTBI)
| Drug(s) | Duration | Total Doses |
|---|---|---|
| Isoniazid (INH)* and Rifapentine (RPT)† | 3 months | 12 |
| Rifampin (RIF)§ | 4 months | 120 |
| Isoniazid (INH)* and Rifampin)§ | 3 months | 90 |
| Isoniazid (INH) | 6 months | 180 |
What are the black box warnings of INH?
Isoniazid is contraindicated in patients who develop severe hypersensitivity reactions, including drug- induced hepatitis; previous isoniazid-associated hepatic injury; severe adverse reactions to isoniazid such as drug fever, chills, arthritis; and acute liver disease of any etiology. See the boxed warning.