What drugs interact with thiazides?
What drugs interact with thiazides?
Thiazides are diuretics, known to interact with drugs such as digoxin, flecainide, and dofetilide pharmacodynamically through thiazide-induced hypokalemia, hyponatremia, and hypovolemia respectively.
What can I monitor with hydrochlorothiazide?
Monitor daily weight, intake and output ratios, amount and location of edema, lung sounds, skin turgor, and mucous membranes. Assess patient for anorexia, muscle weakness, numbness, tingling, paresthesia, confusion, and excessive thirst.
What is the antidote for diuretics?
Fludrocortisone is used as a third-line agent in patients for whom treatment with diuretics, sodium bicarbonate, and dietary measures has failed. It promotes increased reabsorption of sodium and loss of potassium from renal distal tubules.
How is hydrochlorothiazide administered?
Hydrochlorothiazide comes as a tablet, capsule, and solution (liquid) to take by mouth. It usually is taken once or twice a day. When used to treat edema, hydrochlorothiazide may be taken daily or only on certain days of the week.
What drugs should not be taken with diuretics?
Some medications that might interact with a diuretic include:
- cyclosporine (Restasis)
- antidepressants such as fluoxetine (Prozac) and venlafaxine (Effexor XR)
- lithium.
- digoxin (Digox)
- other drugs for high blood pressure.
Do diuretics affect other medications?
Co-prescription of diuretics with antihypertensive agents, potassium, magnesium or acid salts, probenecid, quinidine, anticoagulants, lithium, cardiac glycosides or other diuretics can result in both beneficial and adverse interactions.
When do you check labs after hydrochlorothiazide?
MODERATE AND HIGH RISK PATIENTS (see above) – check at 4 and 10 days. Checks should also be sent after dose increases, and if diuretic doses are increased.
How would you monitor a patient on a diuretic?
Monitoring diuretics
- Check renal function and electrolytes within five days of starting and then every 5-14 days, depending on an individual’s stability.
- Monitor weight and hydration status and, where diuresis is extensive, consider earlier testing of renal function.
What nursing actions should be implemented when administering a diuretic?
Administer intravenous diuretics slowly to prevent severe changes in fluid and electrolytes. Administer oral form early in the day to prevent increased urination during sleep hours. Monitor patient response to drugs through vital signs, weight, serum electrolytes and hydration to evaluate effectiveness of drug therapy.
What are the 3 types of diuretics?
There are three types of diuretics:
- Thiazide.
- Loop.
- Potassium sparing.
What should you avoid when taking hydrochlorothiazide?
Hydrochlorothiazide may interact with other medications
- Barbiturates. If you take these drugs with hydrochlorothiazide, your blood pressure may be lowered too much.
- Lithium.
- Blood pressure drugs.
- Cholesterol-lowering drugs.
- Corticosteroids.
- Diabetes drugs.
- Narcotics.
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
When is the best time to take blood pressure medicine hydrochlorothiazide?
If you are to take a single dose a day, take it in the morning after breakfast. If you are to take more than one dose a day, take the last dose no later than 6 p.m., unless otherwise directed by your doctor.
Do diuretics interact with other medications?
Drug interactions Some medications that might interact with a diuretic include: cyclosporine (Restasis) antidepressants such as fluoxetine (Prozac) and venlafaxine (Effexor XR) lithium.
When are diuretics contraindicated?
Diuretics are contraindicated in patients with known drug hypersensitivity and those with electrolyte imbalance. They should be used cautiously in anyone with renal dysfunction, as changes in blood flow and kidney perfusion may further compromise a diseased kidney.
For which laboratory result should the nurse monitor in a patient receiving hydrochlorothiazide?
Use with caution in severe renal disease. Patients who are taking thiazide diuretics should be monitored for electrolyte depletion, dehydration, weakness, hypotension, renal impairment, and hypersensitivities.
What do you monitor on a diuretic?
Monitoring diuretics
- Check renal function and electrolytes within five days of starting and then every 5-14 days, depending on an individual’s stability.
- Monitor weight and hydration status and, where diuresis is extensive, consider earlier testing of renal function.
What should you check before giving diuretics?
Assess patient for anorexia, muscle weakness, numbness, tingling, paresthesia, confusion, and excessive thirst. Notify health care professional promptly if these signs of electrolyte imbalance occur. Hypertension: Monitor BP and pulse before and during administration.
What assessments should a nurse do before and after administering a diuretic?
Nursing Considerations Monitor weight, intake, output, and serum electrolyte levels. Monitor blood glucose levels (some agents may cause hyperglycemia). Follow blood urea nitrogen and creatinine levels regularly. Administer diuretics in the morning to prevent nocturia.
What should I monitor before giving diuretics?
Assess fluid status throughout therapy. Monitor daily weight, intake and output ratios, amount and location of edema, lung sounds, skin turgor, and mucous membranes. Assess patient for anorexia, muscle weakness, numbness, tingling, paresthesia, confusion, and excessive thirst.
What are the 5 classes of diuretics?
There are five classes of diuretics: thiazides and thiazide-like diuretics; loop diuretics; carbonic anhydrase inhibitors; potassium-sparing diuretics; and osmotic diuretics.
What is medication reconciliation and how does it work?
Medication reconciliation begins with collecting a current medication list. The medication list should include all medications (prescriptions, over-the-counter, herbals, supplements, etc.) and their dose, route, frequency, and indication.
What is triazide Dyazide?
Triazide is commonly prescribed for adults with high blood pressure. Medical experts generally discourage administering Dyazide to children under the age of 12 years, except for conditions that have proven resistant to conventional antihypertensive treatments.
Is there a generic version of triazide?
Triazide is one of the many generic names for Dyazide, powerful antihypertensive medicine that belongs in the Thiazide Combos class of drugs. Triazide is commonly prescribed for adults with high blood pressure.
When should you reconcile your medication list?
Many organizations have a process in place that calls for reviewing the patients’ medication list at every primary care visit and within 24 hours of an inpatient admission. High-risk medications such as antihypertensives, antiseizures, and antibiotics may need to be reconciled sooner, for example, within 4 hours of admission.