What chemicals can cause hearing loss?

What chemicals can cause hearing loss?

Common Chemicals Create Risk for Hearing Loss

  • Benzene – plastics, paints, cleaning agents, cigarette smoke.
  • Carbon disulfide – pesticides.
  • Carbon monoxide – cigarette smoke, welding, gasoline-powered tools and vehicles.
  • Styrene – plastics, insulating material.

Can chemicals make you deaf?

Substances including certain pesticides, solvents, and pharmaceuticals that contain ototoxicants can negatively affect how the ear functions, causing hearing loss, and/or affect balance. The risk of hearing loss is increased when workers are exposed to these chemicals while working around elevated noise levels.

What is the following ototoxic chemicals as per OSHA?

Carbon disulfide, n-hexane, toluene, p-xylene, ethylbenzene, n-propylbenzene, styrene and methylstyrene, trichloroethylene.

What are ototoxic compounds?

Ototoxic chemicals are chemicals that result in hearing loss. Introduction. It is well documented that occupational noise exposure is a significant health hazard that leads to permanent noise-induced hearing loss (NIHL) and we have the National Exposure Standard for Occupational Noise to deal with this.

What toxins cause tinnitus?

Aspartame and monosodium glutamate (MSG) are neurotoxins. Their destructive effects include damaging the auditory cortex, where sound is processed.

Which drugs are ototoxic?

List of Ototoxic Medications

  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), including aspirin, ibuprofen, and naproxen.
  • Certain antibiotics, including aminoglycosides.
  • Certain cancer medications.
  • Water pills and diuretics.
  • Quinine-based medications.

What toxins cause ringing in ears?

Ototoxins are chemicals which can damage hearing and can cause mild to severe hearing loss, tinnitus (ringing in the ears), or deafness. An ototoxin can be ingested, absorbed, or inhaled into the body.

How does ototoxic drugs affect hearing?

What are the effects I may notice from ototoxic medications? Usually the first sign of ototoxicity is ringing in the ears (tinnitus). Over time, you may also develop hearing loss. This hearing loss may go unnoticed until your ability to understand speech is affected.

Is ototoxic tinnitus reversible?

Certain prescription drugs can, over time, have an ototoxic effect on your hearing, causing hearing loss and ear ringing from tinnitus. Ototoxicity may be reversible or may be permanent, depending on the type of medication used, dosage and duration of treatment.

What are the most ototoxic drugs?

The most common reported ototoxic drugs in clinical use are aminoglycoside antibiotics, macrolide antibiotics, salicylates, chemotherapeutic agents such as cisplatin, loop diuretics, antimalarials, non-steroidal anti-inflammatory drugs (NSAIDs), quinine, and acetaminophen (Rybak & Ramkumar, 2007; Tabuchi et al., 2011; …

What enzyme causes tinnitus?

These findings suggest that tinnitus patients were found to be exposed to more oxidative stress. Elevated serum prolidase enzyme activity and oxidative stress index levels may have a role in the pathogenesis of tinnitus.

Can GABA supplements help tinnitus?

GABA (gamma-aminobutyric acid) is a brain neurotransmitter that inhibits electrical activity and reduces tinnitus and other conditions, such as anxiety, depression and epileptic seizure. Over the long-term however, these medications lose their effectiveness, requiring higher dosages or even different medications.

Can preservatives cause tinnitus?

Sulfite – A food preservative found in chocolate, bacon, wine, and dried fruit, for those who are intolerant to sulfite, ingesting these foods can increase tinnitus symptoms.

What is the most ototoxic drug?

Of all ototoxic drugs, the aminoglycosides are the most vestibulotoxic, although they vary greatly in their differential effects on the vestibular and cochlear systems. Kanamycin, amikacin, neomycin, and dihydrostreptomycin are preferentially cochleotoxic.

What type of hearing loss does ototoxicity cause?

major problems with balance. hearing problems, usually in both ears (called bilateral hearing loss). They may have trouble hearing certain things, from high-pitched sounds to talking if there’s background noise. profound hearing loss (deafness)

How long does ototoxic tinnitus last?

You may see some improvement in 2-6 months. You may have tinnitus (ringing, humming or any abnormal sound in your ear or head) as a result of your ototoxicity. Stress, anxiety and tiredness may cause your tinnitus to become worse.

What are the symptoms of ototoxicity?

What are the Symptoms of Ototoxicity? Damage to the hearing organs can range from mild to profound hearing loss and may include tinnitus (ringing in the ears). If the balance organs are damaged, the individual may experience symptoms ranging from dizziness and nausea to imbalance and blurry vision (oscillopsia).

Is ototoxic hearing loss reversible?

Research continues on ways to prevent ototoxicity or fix the damage it can cause. So far there’s no sure way to reverse it. The good news is that sometimes the ear just needs time to heal. And some kids may have no further hearing or balance problems if they can stop taking the medicine that’s causing their symptoms.

What toxicity causes tinnitus?

Unfortunately, toxicity from salicylates remains a common occurrence in the emergency department (ED). Moreover, it is well known that the development of tinnitus is associated with salicylate use, and its onset has been heralded as an early marker of toxicity.

How do ototoxic chemicals affect hearing loss?

Hearing loss can be even greater with exposure to both ototoxic chemicals and noise than exposure to either noise or the ototoxic chemical alone. 1Many ototoxic substances have a greater-than- additive (e.g., synergistic) effect on hearing loss with noise exposure and in particular with impulse noise.

How do you determine the exposure threshold for ototoxicity?

The exposure threshold for ototoxicity varies for each chemical based on its compound family, properties, exposure route, exposure concentration and duration, synergy with noise, and noise exposure, along with an individual’s risk factors. Which industries are more likely to have ototoxicants?

What is the role of acrylonitrile in the pathophysiology of hearing loss?

Pouyatos B, Gearhart C, Fechter D. Acrylonitrile potentiates hearing loss and cochlear damage induced by moderate noise exposure in rats. Toxicol Appl Pharmacol. 2005;204:46–56.

Do industrial solvents pose an additive risk to hearing?

Its findings showed that a large proportion (23%) of the employees working in a chemical division suffered from hearing impairment, despite their exposure to lower noise levels than other divisions. Based on this type of evidence, researchers have long hypothesized that industrial solvents pose an additive risk to hearing.